Relationship between Gingival Inflammation, Neutrophils Count in both Saliva and Blood in different stages of Pregnant Iraqi Women

Abstract

Neutrophil, plays an important role in innate immune response, that phagocyte
bacteria, will burst of oxygen consumption (respiratory burst), and produce reactive
oxygen type as bactericidal or by produce of lysis enzymes (non oxygen dependent).
Phagocytes are the important factors that play a role in acute inflammatory response
due to their ability to destroy various pathogens efficiently. Gingival changes in
pregnancy have been attributed to changes in sub gingival biofilm related to hormonal
variation.
Aim of the study: To evaluate the neutrophils count in both saliva and blood, also
determined the phagocytic activity of neutrophil in pregnant at different stages and
non-pregnant women the study the association of neutrophile changes with
severity of some oral disease including gingivitis and plaque.
Material and methods: twenty four pregnant women as study group and fourteen
non pregnant women as control group were included in this study. The pregnant
women were following up for three groups according to pregnant stages .Plaque
and gingival indicates. Saliva and blood samples from pregnant women at
different stages and control group (non pregnant women) were obtained and
neutrophils total number was determine by using Neubauer chamber so the
neutrophils number were carried out for all subjects . The phagocytic activities of
neutrophils were examined after challenged the neutrophils with candida albicans
that had been opsonized.
Conclusion: salivary and blood neutrophils counting and phagocytic function are
significantly increase in women at third trimester and positively associated with
the severity of plaque and gingivitis.
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