Salivary antioxidents in relation to caries severity among a group of young adults

Authors

  • Samara Faris Abdel Aziz M.Sc at Almaamon specialized dental health center, Department of Prevention dentistry, Baghdad, Iraq
  • Wesal Ali Jasim Professor at college of Dentistry, Ibn Sina University for Medical and Pharmaceutical Science, Department of Prevention dentistry, Baghdad, Iraq

DOI:

https://doi.org/10.32828/mdj.v19i2.986

Keywords:

Dental caries, salivary superoxide dismutase, total protein, young adults

Abstract

Background: Saliva represents the body's stages of toxicological, hormonal, immunological, and markers of many infectious disease and disorders, so that it's an ideal tool for monitoring oral and systemic health.

Antioxidants help the body's defensive system by reducing oxidative stress.

 

Aims of the study: The study was directed to estimate the carious lesion experience (DMFS) in relation to salivary superoxide dismutase and total protein among adults by age and gender.

 

Materials and methods: Caries experiences was assessed according to DMFS index, after investigation eighty peoples of an age 19-22 years for both genders. Stimulated salivary samples were together and chemically assessed to detect selected salivary antioxidants (superoxide dismutase, total protein), under standardized condition. Total protein and superoxide dismutase were measured by spectrophotometric examination.

 

Results: With not-significant differences, total protein was found to be higher in the caries active group than in the caries free group, but salivary superoxide dismutase was the opposite. with statistically not-significant differences, females had a greater average of the salivary total protein than men, whereas men had a greater average of salivary superoxide dismutase than females. the first group (19-20 years) had a not-significant greater average salivary total protein and salivary superoxide dismutase than the second group (21-22 years).

Conclusion: Salivary superoxide dismutase is the important factor in dental caries prevention. As a result, alterations in salivary content are crucial in the development and progression of dental caries.  

References

Lima DP, Diniz DG, Moimaz SA, Sumida DH, Okamoto AC. Saliva: reflection of the body. Int J Infect Dis 2010; 14(3): 184-8.

Humphrey SP, Williamson RT. A review of saliva: normal composition, flow, and function. J Prosthet Dent 2001; 85(2): 162-9.

Brostek AM, Bochenek A J, Walsh LJ. Minimally invasive dentistry: a review and update. Shanghai Kou Qiang Yi Xue 2006; 15(3): 225-49.

Dodwad R, Betigeri AV, Preeti BP. Estimation of total antioxidant capacity levels in saliva of caries-free and caries-active children. Contemp Clin Dent 2011; 2(1): 17-20.

Zahir S, Sarkar S. Study of trace elements in mixed saliva of caries free and caries active children. J Indian Soc Pedod Prev Dent 2006; 24(1): 27-9.

Kadum N. Selected salivary constituents, physical properties, nutritional status in relation to dental caries among (4-5) years old children. J Bagh College of Dentistry 2014; 26(2).

WHO. Oral health surveys basic methods. Geneva, Switzerland, 1987

Tenovuo J, Lagerlöf F. Saliva. In: Thylstrup A, Fejerskov O. Textbook of clinical cariology. 2nd ed. Copenhagen: Munksgaard; 1994:17-43.

Pfaffe T, Cooper-White J, Beyerlein P, Kostner K, Punyadeera C. Diagnostic potential of saliva: current state and future applications. Clin Chem 2011; 57(5): 675-87.

Ozmeric N. Advances in periodontal disease markers. Clin Chim Acta 2004; 343(1-2): 1-16.

Gu F, Lux R, Anderson MH, Del Aguila M, Wolinsky L, Hum W, Shi W. Analyses of Streptococcus mutans in saliva with species-specific monoclonal antibodies. Hybrid Hybridomics 2002; 21(4): 225-32.

Ahmadi-Motamayel F, Goodarzi M, Hendi S, Abdolsamadi, Rafieian N. Evaluation of salivary flow rate, PH, buffering capacity, calcium and total protein levels in caries free and caries active adolescence. J Dent And oral Hygi 2013; 5(4): 35-39.

Tulunoglu O, Demirtas S, Tulunoglu I. Total antioxidant levels of saliva in children related to caries, age, and gender. Int J Paediatr Dent 2006; 16(3): 186-91.

Dodds MW, Johnson DA, Mobley CC, Hattaway KM. Parotid saliva protein profiles in caries-free and caries-active adults. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997; 83(2): 244-51.

Deshpande R, Panval PS, Kulkarnn AA, Gadkari TV. Age-Related Changes of the Human Salivary Secretory Total Protein Complex and Trace Elements in Children between the Age Group of 3-16 Years. J Biomed Sci and Res 2011; 3(1): 362-367.

Vibhakar P, Patankar S, Yadav M, Vibhakar P. Salivary total protein level and their correlation to dental caries. Intern J Oral and Maxillo Patho 2013; 4(3): 13-16.

Roa NS, Chaves M, Gomez M, Jaramillo L. Association of salivary proteins with dental caries in a Colombian population. Acta Odontol Latinoam 2008; 21(1): 69-75.

Banderas-Tarabay J, Zacarías-D’oleire I, Garduño-Estrada R, Aceves-Luna E, González-Begné M. Electrophoretic analysis of whole saliva and prevalence of dental caries. A study in Mexican dental students. Arch Med Res 2002; 33(5): 499-505.

Hegde MN, Hegde A, Ashok A, Shetty S. Biochemical indicators of dental caries in saliva: an in vivo study. Caries Res 2014; 48(2): 170-3.

Shirzad A, Pouramir M, Seyedmajidi M, Jenabian N, Bijani A, Motallebnejad M. Salivary total antioxidant capacity and lipid peroxidation in patients with erosive oral lichen planus. J Dent Res Dent Clin Dent Pros 2014; 8(1): 35-9.

Azizi A, Sarlati F, Parchakani A, Alirezaei S. Evaluation of whole saliva antioxidant capacity in patients with periodontal diseases. Open Journal of Stomatology 2014; 4: 228-231.

Krawczyk D, Sikorska-Jaroszynska M. H., Mielnik-Blaszczak M, Pasternak K, Kapec E, Sztanke M. Dental caries and total antioxidant status of unstimulated mixed whole saliva in patients aged 16-23 years. Adv Med Sci 2012; 57(1): 163-8.

Pereslegina IA. The activity of antioxidant enzymes in the saliva of normal children. Lab Delo 1989; (11): 20-3.

Reznick AZ, Shehadeh N, Shafir Y, Nagler RM. Free radicals related effects and antioxidants in saliva and serum of adolescents with Type 1 diabetes mellitus. Arch Oral Biol 2006; 51(8): 640-8.

Malekirad A, Shariatzadeh SM, Fans A, Ranjbar A. The comparison of total antioxidant capacity of serum and saliva between patients with type-2 diabetes mellitus and control. J Shahrekord Univ Med Sci 2005; 7(3): 69-74.

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Published

30.12.2023

How to Cite

Faris Abdel Aziz, S., & Ali Jasim, W. . (2023). Salivary antioxidents in relation to caries severity among a group of young adults. Mustansiria Dental Journal, 19(2), 311–317. https://doi.org/10.32828/mdj.v19i2.986