The assessment of gingival changes in children with acute Lymphoblast leukemia before and after chemotherapy - clinical study-

Abstract

Background: The aim of this study was to asses the gingival changes in children with
Acute Lymphoplastic Leukemia (ALL) before and after treatment.
Material and method: The sample consist of (15) children with ALL (the age range
was 7-13 years with an average of 10 years of age). They were newly diagnosed.
The patients were examined three times: 1st visit , before starting with
chemotherapy (day 0) , 2nd visit , after 15 days from using chemotherapy (day
15) , 3rd visit after 30 days from using chemotherapy ( day 30 ) .
The examination included clinical parameters namely plaque index
(PL.I),gingival index (G.I), assessment of gingival enlargement , collection of
gingival cervicular fluid (G.C.F) , bleeding point index and Hematological
parameters namely : white blood cells count (WBC count),platelets count and
hemoglobin level in blood (HB).
Result: There was significant difference (decrease) occurred in G I and point index
( p < 0.05 ) in day 30 in compare to day 0. The intimate correlation of clinical
parameter correlation of clinical parameter (C P) in day 0 was with systemic
factor while in day 30, was with local factor (plaque)
Conclusion: There was a significant improvement in gingival health status in day 30
compared to day 0 , the intimate correlation of ( CP ) in day 0 was with systemic
factor but in day 30 was with local factor with less extend to systemic factor.