Effect of ascorbic acid supplementation on skin wound healing

Abstract

Ascorbic acid is essential for proper synthesis of collagen fiber and intercellular
.ground substance of connective tissue
Objective of this study was to determine the effect of ascorbic acid supplementation
mg once daily for l0 days in the treatment of wound skin incision about 2cm in555
.length and 4mm in depth
Thirteen albino rabbit were used in this study (eight rabbits represent experimental
.)group while five represent as a control group
The result of general histological observation revealed rapid and active healing
process through complete epithelization of the surface of incision site and colla enous
g . .
fibrous tissue formation in the incision wound of animals with ascorbic acid
administration while in control group incomplete epithelization and incomplete healing of
.connective tissue of skin wound
It was concluded that the administration of ascorbic acid might be sufficient to promote wound healing