Casein Phosphopeptides-Amorphous Calcium Phosphate’s Effect on Microhardness of Teeth Treated With 5% Sodium Fluoride
DOI:
https://doi.org/10.32828/mdj.v21i1.1187Keywords:
NaF, CPP-ACP, remineralization, caries-like lesions, microhardnessAbstract
Background: Dental caries is a common disease among humans. Its significant impact highlights the need to promote the mineralization of early enamel lesions. Numerous materials have been investigated to enhance the mineralization of teeth. Casein phosphopeptides-amorphous calcium phosphate (CPP-ACP), a milk protein with notable qualities associated with teeth mineralization.
Aim of study: To assess CPP-ACP’s effect on the enamel microhardness of teeth treated with 5% sodium fluoride.
Materials and Method: 40 extracted sound upper 1st premolars were utilized in the study. They were subjected to a pH cycle. Then, 20 teeth were subjected to 5% sodium fluoride solution (NaF) and the remaining 20 to deionized water. All teeth were placed in artificial saliva for 24 hours and then treated with 10% CPP-ACP for seven days. Enamel microhardness was evaluated before and after the artificial formation of caries-like lesions, after applying 5% sodium fluoride and deionized water, and after applying CPP-ACP on the previously treated groups.
Results: It was found that 5% NaF was statically significant in elevating the microhardness of the enamel after demineralization (P=0.000), the mean microhardness values post-demineralization was (119.11), while post-remineralization was (195.910) and following the application of CPP-ACP it became (226.100) which is also significant, (P=0.025).
Conclusion: CPP-ACP is an effective material for mineralizing early carious lesions alone, but it performs best when combined with NaF.
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