Cervical Lymph nodes Enlargement in Relation to Thickness of Oral Squamous Cell Carcinoma
DOI:
https://doi.org/10.32828/mdj.v1i1.1097Keywords:
Squamous cell carcinoma, thickness of tumour, lymph nodes, metastasisAbstract
Tumour thickness measurement was evaluated in relation to clinical nodal status on 26 patients with oral squamous cell carcinoma. The measurement estimated on Haematoxylene and Eosin stained microscopic sections of the resection specimen of each case by using a micro - occulmeter on illuminated viewer. The thickness considered the distance between surfaces epithelium from which the invasion started to the deepest invading front. Analysis of clinical data showed that 14 of the cases had palpable lymph nodes, whereas 12 cases had no palpable nodes. It was found that the mean tumour thickness in group with palpable nodes was 9.5 mm. whereas the mean tumour thickness in group with no palpable nodes was 4.5 mm. This difference, statistically, using t-test was highly significant (p < 0.004). It si concluded, therefore, that, tumour thickness as a single structural parameter can help ni the prediction of cervical lymph nodes involvement ni patients with oral squamous cell carcinoma. Thus, an additional method of treatment can be chose following local resection of the tumour
References
- Anneroth G, Batsakis J, Luna M. Review of literature and recommended system of malignancy grading in oral squamous carcinoma. Scand J Dent Res 1987; 95:229-249.
- Breslow A. Thickness cross-sectional areas and depth of invasion in the prognosis o f c u t a n e o u s melanoma.AnnSurg1970; 172:902- 908. Frierson, HF, cooper PH. Prognostic factors in squamous cell carcinoma of the lower lip. Hum.Pathol 1986; 17:346-354.
- Mohit-Tabatabai, MA, Sabel, HJ Rush, BF, Mashberg A. Relation of the thickness of floor of mouth stages I and Il cancers to regional node metastasis. Am J Surg 1986; 152:351- 353.
- Shingaki S, Suzuki 1, Nakagima T, Kawasaki T. Evaluation histopathologic parameters in predicting cervical lymph node metastasis of oral and oropharyngeal carcinomas. Oral Surg Oral Med Oral pathol 1988; 66:683-688.
-6 Fakih AR, Rao RS, Borges AM, Patel, AR. Elective versus therapeutic neck dissection ni early carcinoma of the oral tongue. Am J Surg 1989; 158:309-313.
- Platz H, Fries R, Hudec M. The prognosis relevance of variou s factors at the first admission of the patient. J Maxillofac Surg 1983; 1: 3-12.
- Moore CM, Kuhns JG, Greenberg RA. Thickness as prognosis aid in upper aerodigestive tract cancer. Arch Surg 1986; 121: 1410-1414.
-Spiro RH, Huvos AG, Wong GY, Gnecco CA, strong EW. Predictive value of tumour thickness ni squamous cell carcinoma confined to the tongue and floor of the mouth. Am J Surg 1986; 152: 345-350.
- Jacobs JR, Spiznegel EL, Sessions DG. Staging parameters for cancers of the head and neck. A multifactorial analysis 1985.
- Batch CM, Soonge, SJ Murad TM. A multifactorial analysis of melanoma. I Prognostic factors ni patients with stage I (localized) melanoma. Surg 1979; 86: 343-351.
- Wolmark N, Fisher ER, Wieand S. The relationship of depth of penetration and tumour size to the number of positive nodes ni Dukes c ncer olorectal cancer. Ca 1984; 53:2707-2712. 13- Urist MM, O'Brien CJ, Soonge SJ. Squamous cell carcinoma of the buccal mucosa Analysis of prognostic factors. Am JSurg 1987; 154:411-414.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International License.
