Clinical Outcome of Azithromycin dehydrate used in treatment of acute apical periodontitis and severe chronic marginal gingivitis compared to other antibiotics

Abstract

 Ninety six patient aged between 12 – 50 years attending the college of dentistry ,
Al- mustansyria university and the investigators clinics , they were divided into two
equal groups; 48 Patients suffering acute apical periodntitis ( painful ) were
subjected to different antibiotics after drainage and their prognosis towards nonpainful
chronic apical perioddontitis was observed and were as follows : 29.3% with
Azithromycin, 20.8 % with ampicilline and 29.3% with ampicilline plus
metronidazole with a total of 79.4 % .
The second group, were 48 students aged 12- 20 years suffering from severe
marginal gingivitis ( GI-3 ) and were subjected to different antibiotics after
prophylaxis and some of them were kept on prophylaxis alone and their progress to
mild marginal gingivitis ( G.I.1) was observed and were as follows :20.8 % with
azithromycin , 16.7 % with ampicilline, 22.9 % with ampicilline plus metronidazole
and 20.8 % with prophylaxis and oral hygiene practice alone with a total of 81.2 %
showing no significant difference between prophylaxis alone and those with
prophylaxis and antibiotics .