@article{Albannaa_Al-Dabbagh_Alnema_2018, title={Histopathological evaluation of human amniotic membrane effect on early stage healing of induced defects in rabbit’s oral mucosa}, volume={10}, url={https://mdj.uomustansiriyah.edu.iq/index.php/mdj/article/view/231}, DOI={10.32828/mdj.v10i2.231}, abstractNote={<p>This study aims to investigate the role of using dried Human Amniotic Membrane<br>(dHAM) on rabbit’s oral mucosal wound healing in its early stages. Six male rabbits<br>were used in this study. In each rabbit, two elliptical incisions were done on both sides<br>of tongue dorsum; one of them was left uncovered and the other was covered by<br>dHAM. The animals were divided into two groups with three rabbits each according<br>to the sacrifice periods which were three days and one week. After sacrifice,<br>histopathological examination was performed to assess re-epithelialization and<br>inflammation. Within the first three days, the re-epithelialization was much more<br>faster in dHAM group than that in control one, and the difference between the control<br>and study group was statistically highly significant ( p=0.005 <0.01). Moreover, the<br>rate of inflammatory process show significant difference between the two groups with<br>advantage to HAM group (p =0.046 <0.05). However, after one week, this difference<br>was statistically non-significant ( p =0.317 > 0.05). Human Amniotic Membrane<br>could be considered as an option to enhance oral wound healing especially in its early<br>stages.<br><br></p>}, number={2}, journal={Mustansiria Dental Journal}, author={Albannaa, Dr. Rasha F. and Al-Dabbagh, Dr. Fahad M. and Alnema, Dr. Manar M.}, year={2018}, month={Feb.}, pages={252–258} }